
Find a Cruise
Southern Caribbean Cruise 1 Night • Colón, Panama to Cartagena, Colombia • Serenade of the Seas
Itinerary
Cruise Overview
Day 1 Sat, Apr 18 Colón, Panama Departs at 4:00 pm
Day 2 Sun, Apr 19 Cartagena, Colombia Arrives at 9:00 am
Cruise Overview

Climb aboard Serenade of the Seas for more thrills, chill and wows than you thought you could fit into a vacation. This action-packed ship departs from Colón, Panama on your cruise to Caribbean. Get ready for an epic getaway.
Day 1 Sat, Apr 18, 2026 Colón, Panama Departs at 4:00 pm
Your ship departs promptly at 4:00 pm, so plan to arrive at least 2-3 hours early to account for checking in and boarding protocols. During this time, many of the ship's amenities are open and operating, so feel free to start your vacation early.
Day 2 Sun, Apr 19, 2026 Cartagena, Colombia Arrives at 9:00 am
The cruise might have ended, but there are still some great activities to enjoy in the area. If you flew into this port, be mindful of your departure flight time and plan accordingly.
Your ship:
Serenade of the Seas
Available Rooms
What’s included with your vacation
Your vacation essentials are always included. Quench your thirst with water, coffee, juice and tea options available at no charge. Indulge in many delicious free dining options onboard. You can also enjoy jaw-dropping entertainment like live shows, live music, themed dance parties and more at no additional cost.
Suites come with extra amenities and inclusions.
Click here to learn more- Standard beverages like water, coffee, juice and tea options
- Food and snacks at our cafes and buffets
- Shows, live music, and entertainment
- Most onboard experiences
Snag these upgrades at an additional cost
- World-class dining at speciality restaurants
- Cocktails, specialty coffees, sodas and bottled water
- Wi-Fi to stay connected at sea
- Spa treatments
- Shore excursions
- Professional photography
- Royal Babies and Tots℠ Nursery
- Laundry services